2 Corinthians 12:9 contains God's answer to Paul's repeated prayer for physical relief from his "thorn in the flesh": "My grace is sufficient for thee: for my strength is made perfect in weakness." This is not the answer Paul wanted. He asked for the thorn to be removed three times. The answer was not healing but the presence and sufficiency of God in the condition. This is not a comfortable theology. But it is an honest one, and it refuses to make faith into a cure while also refusing to leave the suffering person without God's company.
The promise of Revelation 21:4 β "no more death, neither sorrow, nor crying, neither shall there be any more pain" β is not set in the present tense. It is a future. It does not deny the present reality of pain. It frames it within a larger story that has a different ending. Paul calls present sufferings "not worthy to be compared" to what is coming (Romans 8:18) β not because the present suffering is small but because what is coming is that much larger.
Commentary is from a charismatic Protestant perspective, drawing on KJV text and public-domain sources including Spurgeon, Andrew Murray, and Matthew Henry.