Psalm 42:5 asks a question that acknowledges the reality of depression without accepting it as the final word: "Why art thou cast down, O my soul? and why art thou disquieted in me?" The Hebrew shaach β "cast down" β means bowed down, stooped, unable to stand upright. The psalmist is asking his own soul why it is in this state β a conversation with the self, not a question God has failed to answer. The resolution offered is not "feel better" but "hope thou in God": an act of will directed at a fixed point when feeling is not available.
Postpartum depression is a physiological condition β hormonal, neurological, physical. 1 Kings 19 records that Elijah's recovery began with sleep and food. The body was treated before the mission was addressed. Seeking medical care, therapy, and medication for postpartum depression is not a substitute for faith. It is the kind of practical, embodied care that God himself prescribed for an exhausted prophet.
Commentary is from a charismatic Protestant perspective, drawing on KJV text and public-domain sources including Spurgeon, Andrew Murray, and Matthew Henry.