Romans 8:35–39 asks a rhetorical question: "Who shall separate us from the love of Christ?" and then works through every possible answer: tribulation, distress, persecution, famine, nakedness, peril, sword. It concludes that nothing — not any of these things, not death, not life, not height or depth — can separate from God's love. Self-harm often grows in the conviction that the pain makes you unworthy of love, or that the behavior itself would disqualify you. Paul's list is meant to be exhaustive. There is no asterisk.
The suffering in Lamentations 3:31–33 is written from inside genuine disaster: "For the Lord will not cast off for ever: But though he cause grief, yet will he have compassion according to the multitude of his mercies." This is not optimism. It is a hard-won theological conclusion written by someone in real darkness. If you are struggling with self-harm, reaching out to a therapist or counselor is wisdom — it is the kind of practical, embodied help that God provides through people, and there is no shame in receiving it.
Commentary is from a charismatic Protestant perspective, drawing on KJV text and public-domain sources including Spurgeon, Andrew Murray, and Matthew Henry.