The idea that setting limits in relationships is unbiblical confuses self-sacrifice with self-destruction. Jesus, who is the model of self-giving love, regularly withdrew from people when needed (Luke 5:16), refused to answer when silence was the right response (Matthew 27:14), and spoke direct, blunt truth to people causing harm (Matthew 23). He loved without being controlled.
Proverbs is direct in ways that polite Christian teaching rarely allows itself to be. "Make no friendship with an angry man; and with a furious man thou shalt not go: Lest thou learn his ways, and get a snare to thy soul" (Proverbs 22:24β25). This is not cold or unloving. It is wisdom that recognizes that patterns are contagious β that prolonged proximity to certain kinds of people reshapes you in ways you may not notice until the reshaping is done.
Romans 16:17 contains one of Paul's least quoted commands: "mark them which cause divisions and offences contrary to the doctrine which ye have learned; and avoid them." Paul permits β requires β avoidance of certain kinds of people. The word is ekklino, to turn away from, to step out of the path of. The same Paul who commands love also commands discernment about who gets access to you.
Commentary is from a charismatic Protestant perspective, drawing on KJV text and public-domain sources including Spurgeon, Andrew Murray, and Matthew Henry.